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 Molecular Markers Associated with Hepatotoxicity. Development of in vitro test system based on human cells
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Molecular Markers Associated with Hepatotoxicity. Development of in vitro test system based on human cells

автор Krzysztof W. издательство Книга по Требованию Органическая химия
Cтраниц 208        мягкая обложка       
Аннотация:Metabolism of drugs and toxic compounds in many cases is different in test animals and humans. Traditionally preclinical toxicological studies are performed on animals. Testing of drugs can be performed for hours or weeks/months to follow acute or chronic toxicity respectively. As a consequence results of toxicological studies in animals can lead to false conclusions and termination of development of drug candidates potentially beneficial to humans and also to continued development of drug candidates that later show to be toxic to humans. This book presents development of an in vitro human cells based test system that is suitable for pre-clinical studies of drugs and assessment of adverse effects of various chemical compounds. The system is based on rotary vessels that simulate growth in microgravity conditions allowing the cells to grow continuously for months and create cell conglomerates that resemble normal liver tissue. Pharmaceutical and, to a lesser degree, most other consumer products are routinely tested for safety.
Автор: Krzysztof W.
Издательство: Книга по Требованию
Год:2009
Цена:
3190 руб
Нет в наличии
Поиск: Molecular Markers Associated with Hepatotoxicity. Development of in vitro test system based on human cells
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Фармакогностичне дослідження надземної частини кульбаби лікарської (taraxacum officinale wigg.) та...

МІНІСТЕРСТВО ОХОРОНИ ЗДОРОВўЯ УКРАЇНИ НАЦІОНАЛЬНА МЕДИЧНА АКАДЕМІЯ ПІСЛЯДИПЛОМНОЇ ОСВІТИ імені П.Л. ШУПИКА Гудзенко Андрій Вікторович УДК 582.923.1 615.451 фармакогностичне дослідження надземної частини кульбаби лікарської ( araxacum offici ale WIGG.) та розробка способів аналізу біологічно активних речовин 15.00.02 - фармацевтична хімія та фармакогнозія АВТОРЕФЕРАТ дисертації на здобуття наукового ступеня кандидата фармацевтичних наук київ - 2008 Дисертацією є рукопис. Робота виконана в Державній установі were developed. I was es ablished, ha ex rac s of leaves a d flowers of Тaraxacum offici ale co cer s o prac ically o oxical subs a ces a d has a i-i flamma ory a d a ioxida ive ac ivi ies. he oppor u i y of usi g chicoric acid, co ai ed i all par s of a Тaraxacum offici ale, as a marker of a da delio a a alysis of pla mix ures was show . Key words: Тaraxacum offici ale flowers, Тaraxacum offici ale leaves, pharmacog os ic i ves iga io , biological ac ive compou ds, s a dardiza io of raw ma erial, s a dardiza io of pla mix ures, a i-i flamma ory ac ivi y, a ioxida ive ac ivi y.
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