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 Structural characterisation of NSAIDS and cyclodextrin-NSAID complexes. A study at the molecular level
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Structural characterisation of NSAIDS and cyclodextrin-NSAID complexes. A study at the molecular level

автор Pamela M. издательство Книга по Требованию Физическая химия
Cтраниц 160        мягкая обложка       
Аннотация:In addition, some insight is provided as to why the popular NSAID, Vioxx®, was pulled off the shelves. Under different thermodynamic and kinetic conditions a chemical substance may crystallise into different crystalline forms (polymorphs). These different species, due to their different crystal structures have different physical properties such as solubility and dissolution rate and therefore the most appropriate polymorph needs to be identified for optimum bioavailability. Non- steroidal anti-inflammatory drugs (NSAIDs) are used for the prevention of pain and inflammation. Since, however, the solubility and bioavailability of NSAIDs are generally poor, encapsulation of these drugs in cyclodextrins was attempted in order to alter their dissolution properties. In the work reported here several NSAIDs, were studied for possible inclusion or novel crystalline phase isolation.
Автор: Pamela M.
Издательство: Книга по Требованию
Год:2009
Цена:
2402 руб
Нет в наличии
Поиск: Structural characterisation of NSAIDS and cyclodextrin-NSAID complexes. A study at the molecular level
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Гражданская война в США

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