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 Stem cell-based therapy of ocular surface diseases. Novel approaches to expansion of adult epithelial stem cells in culture
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Stem cell-based therapy of ocular surface diseases. Novel approaches to expansion of adult epithelial stem cells in culture

автор Ewa M. издательство Книга по Требованию Медико-биологические дисциплины
Cтраниц 84        мягкая обложка       
Аннотация:One emerging surgical strategy for restoring a normal corneal epithelial surface in patients with limbal stem cell (SC) deficiency is transplantation of ex vivo expanded limbal epithelial SC which represents one of the few adult human SC therapies being currently employed. In unilaterally affected patients, this therapeutic approach commonly involves the harvest of a small limbal biopsy from the patient's contralateral healthy eye followed by cell expansion ex vivo and generation of an epithelial sheet on a transplantable carrier. Although successful restoration of the ocular surface occurs in the early postoperative period, the long-term outcome is less satisfactory, most probably due to depletion of limbal SC in culture. In this work an improved culture protocol was established for isolation, enrichment and preservation of limbal epithelial stem and progenitor cells within transplantable cultivated epithelial cell sheets. Furthermore, the work focused on the examination of hair follicles as an alternative autologous SC source and developement of a new more promising therapy for patients with bilateral limbal SC deficiency.
Автор: Ewa M.
Издательство: Книга по Требованию
Год:2010
Цена:
2361 руб
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Поиск: Stem cell-based therapy of ocular surface diseases. Novel approaches to expansion of adult epithelial stem cells in culture
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Получение тонкопленочных электретов на основе фторопласта - 4 и изготовление приборов на их...

Аннотация. В дипломном проекте рассмотрен электретный эффект в пленках фторопластата - 4 толщиной 10 мкм с односторонней металлизацией алюминием. Разработана новая ячейка для электретирования в плазме газового разряда. Было проведено исследование влияния технологических факторов на получение и характеристики электретов. Для подтверждения модели формирования заряда проведены оптические исследования электретированных пленок. На основе полученных мембран разработан и изготовлен макет электретного датчика для экспериментального комплекса исследования проходимости бронхов. Abs rac . he elec re eflo films wi h 10 m hick ess wich is co sidered i gradua io paper o e side Al ju c io . e moder cell for plasm-e haced vapo elec re io is elabora ed. he s udy of i flue ce of ech ological fac ors o process of charge forma io model are followed. O base of he ob ai i g films model of elec re chip for experime al complex for exemi a io of bro chial ra spor is elabora ed. Содержание. Введение. 1.Обзор литературы. 5 1.1.Электреты. Общие сведения. 5 1.2.Методы получения электретов. 5 1.3.Обзор существующих моделей электретного эффекта 17 1.3.1.Модель заряда электрета на основе неполярного диэлектрика. 22 2.Технико-экономическое обоснование проекта 33 3.Экспериментальная часть 34 3.1.Методика получения электретов в плазме газового разряда 34 3.2.Установка для импульсного электретирования 37 3.3.Конструкция ячейки для электретирования 40 3.4.Работа установки 42 3.5.Методика измерения заряда электрета 43 3.6.Исследование влияния режимов электретирования на характеристики электретов 47 3.7.Оптические исследования электретированых пленок фторопласта - 4 62 3.8.Области применения электретного микрофона 65 3.9. Проектирование электретного датчика 67 3.9.1.Расчет чувствительности микрофона 67 3.9.2.Разработка конструкции датчика 13 3.10.Выводы по экспериментальной части 77 4.Экономическая часть 78 5.Безопасность и экологичность проекта 87 6.Заключение 95 7.Библиографический список 96 Введение.
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