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 Motor neuron regeneration in the spinal cord of adult zebrafish.
Наименование:

Motor neuron regeneration in the spinal cord of adult zebrafish. (HAMILTON, 1822)

автор Michell M.R. издательство Книга по Требованию Органическая химия
Cтраниц 100        мягкая обложка       
Аннотация:Using immunohistochemical markers and transgenic reporter fish for motor neurons, this study demonstrates that large differentiated motor neurons are transiently lost after a spinal lesion, suggesting that these cells undergo cell death after a lesion and are replaced. Indeed, a massive and transient increase in the number of small, undifferentiated motor neurons was observed. Proliferation and lineage tracing studies indicated significant proliferation only at the spinal ventricle and that a subset of olig2 expressing ependymo-radial glial cells are the motor neuron progenitor/stem cells in the lesioned spinal cord. Overall, this study demonstrates that adult zebrafish are capable of motor neuron regeneration from endogenous progenitor/stem cells and that sonic hedgehog is an important regulator of motor neuron regeneration. This study establishes adult spinal cord lesion as a model system for motor neuron regeneration, which may ultimately help to find ways to promote motor neuron regeneration also in human conditions, such as spinal cord injury or motor neuron disease. Adult zebrafish, in contrast to mammals, are capable of functional spinal cord regeneration.
Автор: Michell M.R.
Издательство: Книга по Требованию
Год:2010
Цена:
2361 руб
Нет в наличии
Поиск: Motor neuron regeneration in the spinal cord of adult zebrafish. (HAMILTON, 1822)
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Детская нейрохирургия: врожденные аномалии

Исходы: Основной целью операции является предотвращение дальнейшего прогрессирования симптоматики (эффективность более чем 95%). Имеющиеся же симптомы в большинстве случаев остаются на предоперационном уровне. Улучшение наблюдается не более чем у 20% больных. Поэтому очень важно, чтобы при появлении первых же симптомов больной был консультирован нейрохирургом. “Расщепленный спинной мозг” – выделяют два варианта этой патологии: диастематомиелия – когда костный “шип” (см.МРТ изображение) разделяет как спинной мозг, так и дуральный мешок на два отдельных “рукава”; дипломиелия – когда сам спинной мозг разделен на две половинки фиброзным тяжом и, все это находится в едином дуральном мешке. Симптоматика, показания к операции и результаты аналогичны описанным выше в разделе “Фиксированный спинной мозг” (“ e he red cord”). Операция состоит из “удаления шипа” и освобождения спинного мозга (“u e heri g”) путем иссечения конечной нити.   SPI A BIFIDA APER A Миеломенингоцеле(ММ) – врожденный дефект формирования позвоночника, оболочек и самого спинного мозга и его корешков.
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