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 From Parallel Mini-Scale Screening to Fermenter Up-Scaling Enzymatic Baeyer-Villiger Oxidation for Natural Product Synthesis.
Наименование:

From Parallel Mini-Scale Screening to Fermenter Up-Scaling Enzymatic Baeyer-Villiger Oxidation for Natural Product Synthesis.

издательство Книга по Требованию Экономическая теория
Cтраниц 200        мягкая обложка       
Аннотация:Baeyer-Villiger oxidation using biocatalysts represents a powerful methodology for the one-step asymmetric synthesis of chiral lactones. This work spans from biocatalyst assignment within screening protocols to up-scaling of the process to, ultimately, applying this biotransformation in the synthesis of natural compounds. Due to a large number of different Baeyer-Villiger monooxygenases (BVMOs) with so far unknown biocatalytic properties the development of an efficient screening methodology based on microscaled whole-cell biotransformations became mandatory. The fermentation optimization of whole-cell mediated Baeyer-Villiger oxidation was the next logical step. The introduction of enzymes as catalysts into synthetic organic chemistry opened access to many new and highly enantioselective transformations. Several critical parameters of the fermentation process were optimized. A two-in-one in situ substrate feeding and product removal concept (SFPR) using an adsorbent resin and a recombinant E. coli strain was elaborated. This book is a very valuable contribution to the scientific community especially for people which are interested in the field of applied biocatalysis.
Издательство: Книга по Требованию
Год:2008
Цена:
2783 руб
Нет в наличии
Поиск: From Parallel Mini-Scale Screening to Fermenter Up-Scaling Enzymatic Baeyer-Villiger Oxidation for Natural Product Synthesis.
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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Параллельный интерфейс: LPT-порт

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