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 Effects of Src-inhibitors on osteoclasts in vitro. Concerning inhibitory activity on osteoclastic bone resorption, viability of osteoclasts, and their differentiation from precursors
Наименование:

Effects of Src-inhibitors on osteoclasts in vitro. Concerning inhibitory activity on osteoclastic bone resorption, viability of osteoclasts, and their differentiation from precursors

автор Stefanie S. издательство Книга по Требованию Медико-биологические дисциплины
Cтраниц 80        мягкая обложка       
Аннотация:Disturbances in the process of remodelling can give rise to common bone disorders such as osteoporosis. Also the effects on viability and the number of osteoclasts were examined. The Src inhibitor substances SI35, SI34, SI83, SI24, and S2 were studied for their effects on osteoclasts and bone remodelling in vitro. All of the tested substances had an effect on the differentiation of osteoclasts derived from mouse coculture. The aim was to investigate their functions on osteoclastic bone resorption activity and osteoclast differentiation from precursors. Many people suffer from osteoporosis and other bone diseases and therefore it is important to search for effective pharmaceutical compounds. The human skeleton is continuously regenerated in order to repair damages of the bone and to maintain homeostasis. In Osteoporosis the resorption of bone exceeds the formation of new bone resulting in loss of bone mass and fractures. Src inhibitor substance SI83 had the strongest inhibitory activity – in the resorption assays with coculture- derived osteoclasts as well as in the resorption assays with rabbit osteoclasts.
Автор: Stefanie S.
Издательство: Книга по Требованию
Год:2008
Цена:
2007 руб
Нет в наличии
Поиск: Effects of Src-inhibitors on osteoclasts in vitro. Concerning inhibitory activity on osteoclastic bone resorption, viability of osteoclasts, and their differentiation from precursors
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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