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 A Proteomic Approach for Bordetella Pertussis. Identification of the New Immunogenic Proteins of Bordetella pertussis, the Causative Agent of Whooping Cough, by Immunoproteomics
Наименование:

A Proteomic Approach for Bordetella Pertussis. Identification of the New Immunogenic Proteins of Bordetella pertussis, the Causative Agent of Whooping Cough, by Immunoproteomics

автор EMRAH A. издательство Книга по Требованию Книги
Cтраниц 120        мягкая обложка       
Аннотация:In the present study, we report first immunoproteomics analysis to identify candidate antigens of B. pertussis for vaccine development. Whooping cough is presently one of the ten most common causes of death from infectious diseases and reported by the World Health Organisation (WHO) to cause 50 million cases and 350000 deaths worldwide per year. The term proteome, in analogy to the term genome, was coined to describe the complete set of proteins that an organism has produced under a defined set of conditions. Bordetella pertussis is the etiologic agent of whooping cough. Proteomics has been used to identify novel bacterial vaccine candidates against several human pathogens. Different sera from mice, which were immunized or challenged with B. pertussis, were analyzed for reactivity by Western blot against whole cell extracts of B. pertussis Tohama and Saadet strains separated by 2-DE. Much of information about immunogenic component can be derived from proteomics coupled to Western blotting, namely immunoproteomics. The genus Bordetella contains several pathogenic species generally associated with upper respiratory tract infections in warm-blooded animals.
Автор: EMRAH A.
Издательство: Книга по Требованию
Год:2009
Цена:
2007 руб
Нет в наличии
Поиск: A Proteomic Approach for Bordetella Pertussis. Identification of the New Immunogenic Proteins of Bordetella pertussis, the Causative Agent of Whooping Cough, by Immunoproteomics
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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Evaluating the GPRS Radio Interface for Different Quality of Service...

I co ras o he models developed i , our approach addi io ally represe s he mobili y of users hrough arrival ra es of ew GSM a d GPRS users as well as ha dover ra es of GSM a d GPRS users from eighbori g cells. Fur hermore, we co sider users wi h differe QoS profiles modeled by a weigh ed fair queuei g scheme accordi g o . he remai der of he paper is orga ized as follows. Sec io 2 describes he basic GPRS e work archi ec ure, he radio i erface, a d differe QoS profiles, which will be co sidered i he simula or. I Sec io 3 we describe he sof ware archi ec ure of he GPRS simula or, de ails abou he mobili y of GSM a d GPRS users, he way we modeled quali y of service profiles, a d he workload model we used. Resul s of he simula io s udies are prese ed i Sec io 4. We provide curves for average carried raffic a d packe loss probabili ies for differe cha el alloca io schemes a d packe priori ies as well as curves for average hroughpu per GPRS user.3 he Simula io Model We co sider a clus er comprisi g of sever hexadiago al cells i a i egra ed GSM/GPRS e work, servi g circui -swi ched voice a d packe -swi ched da a calls. he performa ce s udies prese ed i Sec io 4 were co duc ed for he i ermos cell of he seve cell clus er.
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