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 Interleukin-1 Genetic polymorphisms in African ancestry. Prevalence and association with chronic periodontitis in the Xhosa population of South Africa
Наименование:

Interleukin-1 Genetic polymorphisms in African ancestry. Prevalence and association with chronic periodontitis in the Xhosa population of South Africa

автор TAREQ A. издательство Книга по Требованию Научно-популярная литература
Cтраниц 116        мягкая обложка       
Аннотация:Studies designed to estimate the genetic risk for periodontitis indicated that both smoking habits and ethnicity are confounding factors. A specific polymorphism in the interleukin-1 gene cluster is associated with severity of periodontitis. The prevalence of periodontitis appears to vary between populations with different genetic backgrounds, and findings from one ethnic group may not be extrapolated to other ethnic groups. Bacterial pathogens are the primary aetiologic factors in periodontal disease. The disease process is modified by several risk factors, including; smoking, systemic diseases and genetic influences. Perusal of the literature indicates that this is the first study to evaluate the prevalence of the interleukin- 1 composite genotype and its association with chronic periodontal disease in a population of African ancestry. The study results might be useful to interested researchers and students alike. Host response to periodontal disease is a protective as well as a destructive process and the role of pro- inflammatory cytokines, notably interleukin-1 in bone resorption and attachment loss has been reported.
Автор: TAREQ A.
Издательство: Книга по Требованию
Год:2009
Цена:
2007 руб
Нет в наличии
Поиск: Interleukin-1 Genetic polymorphisms in African ancestry. Prevalence and association with chronic periodontitis in the Xhosa population of South Africa


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