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 New Strategies in Quantitative Structure-Activity Relationships. Applications to Adenosine Receptor Ligands
Наименование:

New Strategies in Quantitative Structure-Activity Relationships. Applications to Adenosine Receptor Ligands

автор Alice B.K. издательство Книга по Требованию Медико-биологические дисциплины
Cтраниц 148        мягкая обложка       
Аннотация:Due to the wide range of possible applications of QSAR methods, this book is addressed not only to QSAR modelers working in the medicinal chemistry field, but to all modelers who desire to predict biological, as well as toxicological, physico-chemical and many other properties. QSAR represents an important tool in drug design, allowing early prediction of the biological activity of newly designed molecules. In both cases, attention was focused on the validation of the obtained models, especially concerning their goodness-of-fit, robustness, predictive ability and applicability domain. Quantitative Structure-Activity Relationships (QSAR) is a technique used to establish correlations between chemical structures and a given target property, such as the affinity at a given receptor. In this work, QSAR methods were applied to ligands for the adenosine receptors, which possess many therapeutic potentials. Two different approaches were attempted: on one hand the rigorous observation of QSAR guidelines provided by the Organisation for Economic Co-operation and Development (OECD) in each step of model development, on the other hand an innovative and more dynamic method.
Автор: Alice B.K.
Издательство: Книга по Требованию
Год:2009
Цена:
2415 руб
Нет в наличии
Поиск: New Strategies in Quantitative Structure-Activity Relationships. Applications to Adenosine Receptor Ligands
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Russia and the international economy

Alo gside wi h o her provisio s his program shall embrace cus oms ariff ra es pla ed for he year i ques io as well as he ba d of heir possible fluc ua io , hus maki g he foreig rade more predic able. he Gover me has he righ o i roduce expor a d impor qua i a ive res ric io s o a io al securi y grou ds, o comply wi h i er a io al agreeme s or o pro ec he domes ic marke , however, hese measures shall be a ou ced o less ha 3 mo hs prior o heir ac ual i roduc io . he law e visages a possibili y o i roduce s a e mo opoly for rade i cer ai produc s. I his case a special procedure of lice si g impor a d expor opera io s exclusively o s a e-ow ed e erprises shall be applied.  As he above me io ed law was effec ua ed, he Commissio of he RF Gover me o Safeguard Measures i Foreig rade became fully legi ima e a d i December i received "Procedures of I ves iga io Prior o Applica io of Safeguard Measures" approved by he MFER (Russ.abbr. MVES). A possibili y o apply safeguard measures agai s compe i ive impor ed produc s complies wi h usual prac ices applicable i he world rade.
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