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 Tools for Breast Cancer Detection and Therapy Recombinant Anti-MUC1 and Anti-ErbB2 Antibodies
Наименование:

Tools for Breast Cancer Detection and Therapy Recombinant Anti-MUC1 and Anti-ErbB2 Antibodies: Recombinant Antibodies for Cancer Immunotherapy.

автор Yariv M. издательство Книга по Требованию Органическая химия
Cтраниц 200        мягкая обложка       
Аннотация:Recombinant antibodies have made a tremendous impact on biomedical research and are increasingly being used as clinical diagnostic and therapeutic reagents. This work provides evidences that bivalent antibody-toxin molecules (200 kDa) are superior to the corresponding recombinant monovalent immunotoxins (69 kDa) in killing tumor cells in culture and human carcinoma xenografts in nude mice, suggesting that higher avidity and longer residence time may outweigh tumor penetration. This book evaluates the potential of recombinant derivatives of an anti-MUCI and an anti- ErbB2 Mabs to serve as tools for breast cancer detection and therapy. To explore the potential of Mabs in antibody-targeted cancer therapy, a novel IgG-toxin immunoconjugate is described. The discovery of the tumor markers, opened a new era in the development of antibody-targeted cancer therapy. Although many challenges must be addressed before the approaches mentioned in this book become standard tools for cancer therapy, continued research in this area will feed the clinical product pipeline and play an increasingly important role in finding the "magical bullet" for cancer.
Автор: Yariv M.
Издательство: Книга по Требованию
Год:2009
Цена:
2783 руб
Нет в наличии
Поиск: Tools for Breast Cancer Detection and Therapy Recombinant Anti-MUC1 and Anti-ErbB2 Antibodies: Recombinant Antibodies for Cancer Immunotherapy.


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