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 Cellular Regulation of Glutamate Receptors in Central Neurons. Intracellular Signaling, Receptor Trafficking, Protease Proteolysis
Наименование:

Cellular Regulation of Glutamate Receptors in Central Neurons. Intracellular Signaling, Receptor Trafficking, Protease Proteolysis

автор Eunice Y. издательство Книга по Требованию Органическая химия
Cтраниц 188        мягкая обложка       
Аннотация:Neurological disorders, such as schizophrenia, depression and stroke, result from aberrant glutamate signaling in certain brain regions. This book dissects three cellular aspects of how glutamate receptors are modulated in cortical neurons: neuromodulator-mediated signaling, cytoskeleton-based delivery of ion channels and protease-dependent degradation of receptors. Therefore, research on glutamate receptor is of particular interest in understanding brain function under normal and pathological conditions. Changes in the levels or localization of glutamate receptor profoundly affect synaptic activity and signal transduction. Our brain houses the network of 10 billion neurons, and glutamate is the major neurotransmitter mediating rapid and excitatory synaptic transmission. Knowledge here may shed light on identifying new drug targets for treating brain disorders that associated with impaired glutamate system. Interestingly, glutamate receptor channels travel between intracellular compartments in response to various extracellular stimulations.
Автор: Eunice Y.
Издательство: Книга по Требованию
Год:2009
Цена:
2783 руб
Нет в наличии
Поиск: Cellular Regulation of Glutamate Receptors in Central Neurons. Intracellular Signaling, Receptor Trafficking, Protease Proteolysis
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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