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 Genetic background and the response to anaesthetics and analgesics. A pharmacogenetic approach to identify the causes of strain-specific responses in rat and rabbit
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Genetic background and the response to anaesthetics and analgesics. A pharmacogenetic approach to identify the causes of strain-specific responses in rat and rabbit

автор Harutyun A. издательство Книга по Требованию Научно-популярная литература
Cтраниц 124        мягкая обложка       
Аннотация:In the rats it was demonstrated that buprenorphine administration did not only result in strain-specific responses to its analgesic but also to its behavioural effects. This book will aid medical and veterinary researchers in the development of tailored anaesthesia. Both in the rat and rabbit,significant strain differences were observed in the response to a variety of commonly used anaesthetics and analgesics in (laboratory animal) medicine. This response was then genetically analyzed and candidate genes were identified on the rabbit genetic map. Parameters for a genetic analysis were thus provided to identify candidate genes involved in this variability. In the studies described in this book, rabbit and rat inbred strains were used to identify differences in response to anaesthetics and analgesics. Besides environmental influences, genetic factors might be involved in this phenomenon. The difference in response to medetomidine between two rabbit strains was linked to differences in the anaesthetic’s biotransformation rate. The response of (laboratory) animals to anaesthetics and analgesics shows intraspecies variability.
Автор: Harutyun A.
Издательство: Книга по Требованию
Год:2009
Цена:
2415 руб
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Поиск: Genetic background and the response to anaesthetics and analgesics. A pharmacogenetic approach to identify the causes of strain-specific responses in rat and rabbit
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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