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 Host and Pathogen Sensory Systems as Targets for Therapeutic Intervention. The Roles of Toll-Like Receptor 9 and PhoPQ in Host and Pathogen Defense Mechanisms
Наименование:

Host and Pathogen Sensory Systems as Targets for Therapeutic Intervention. The Roles of Toll-Like Receptor 9 and PhoPQ in Host and Pathogen Defense Mechanisms

автор Jason K. издательство Книга по Требованию Другие общетехнические дисциплины
Cтраниц 220        мягкая обложка       
Аннотация:The work presented here considers mechanisms for the improvement of these treatments through optimization (in the case of CpGs) or alternatively minimization (in the case of HDPs) of the interactions of these ligands with sensory receptors. In this capacity, host defense peptides (HDPs) and synthetic Toll-like receptor 9 (TLR9) ligands have the greatest demonstrated potentials. A new paradigm for the treatment of infectious disease is through the modulation of innate immune responses. Alternatively, a methodology for the characterization of HDPs is described that permits discrimination and quantification of the distinct, but related, behaviors of direct antimicrobial activity and PhoQ ligand potential and provides a rational basis for peptide selection with greater therapeutic potential and minimized potential for initiation of bacterial resistance. From the perspective of TLR9, a model is proposed in which TLR9 activation is mediated specifically by CpG-containing ligands while sensitivity of the receptor is modulated by the absolute concentration of nucleic acids in a sequence-independent fashion.
Автор: Jason K.
Издательство: Книга по Требованию
Год:2008
Цена:
3233 руб
Нет в наличии
Поиск: Host and Pathogen Sensory Systems as Targets for Therapeutic Intervention. The Roles of Toll-Like Receptor 9 and PhoPQ in Host and Pathogen Defense Mechanisms
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Лингвистика

Их конкретное содержание определяется лицами, носящими данные имена, однако они имеют свойство выполнять не только назывные функции, но и обозначать какое-нибудь качество, свойство, характерные черты личности вообще. Здесь можно привести следующий отрывок: - A perso ca be - Miserable like he li le ma ch girl - Alike wi h wome a d fas wi h gu like James Bo d Маленькая девочка, продающая спички на улице (образ, сложившийся в английской литературе 19 века) олицетворяет собой лишения и страдания. Наоборот Джеймс Бонд - суперагент 007, с ним связано представление о супермене, любимце женщин. Однако без знания этого было бы невозможно понять весь смысл, который пытались вложить авторы в эти строки. Требуется знание литературы, истории, традиций Англии. Связь истории и культуры народа с языком особенно ярко проявляется на фразеологическом уровне. Большое число пословиц, поговорок отражают специфические национальные черты, корнями своими уходят в историю народа, его быт, обычаи, традиции. Сравним, например, английские и русские пословицы: Cris mas comes bu o ce a year Не все коту масленица o have o e’s cake a d ea i И волки сыты, и овцы целы A ca may look a a ki g Не боги горшки обжигают Или следующие фразеологизмы A drop i he bucke Капля в море o kill wo birds wi h o e s o e Убить двух зайцев В английском языке имеется большое количество фразеологизмов имеющих литературное происхождение, многие из которых широко применяются в каждодневной разговорной речи.
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