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 Cellular Responses to AIDS-Virus Infection. Understanding the Antiviral Efficacy and Breadth of CD8+ T Lymphocytes against Simian Immunodeficiency Virus
Наименование:

Cellular Responses to AIDS-Virus Infection. Understanding the Antiviral Efficacy and Breadth of CD8+ T Lymphocytes against Simian Immunodeficiency Virus

издательство Книга по Требованию Общая биология
Cтраниц 264        мягкая обложка       
Аннотация:This research should be especially useful for those studying cellular immune responses against AIDS-virus infection. This information may be important in determining the type of CTL epitopes to be targeted in future HIV vaccines. We then examined the antiviral efficacy of these SIV-specific CTL using a novel viral suppression assay. The SIV-infected rhesus macaque is the most widely used animal model for studying HIV infection. Many studies illustrate the important role of CD8+ T lymphocytes, also known as cytotoxic T lymphocytes (CTL), in controlling HIV and simian immunodeficiency virus (SIV) replication. We enhanced the utility of this model by evaluating the breadth of novel, SIV-specific CTL responses in infected macaques. However, the correlates of immune protection remain unknown. With >95% of new infections occurring in low and middle income countries with limited access to antiretroviral therapy, the development of a prophylactic HIV vaccine remains one of the world' s top public health priorities. In 2007, approximately 33 million people were living with HIV/AIDS worldwide, while an estimated 2. 5 million new infections occurred and 2. 1 million AIDS-related deaths.
Издательство: Книга по Требованию
Год:2008
Цена:
3233 руб
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Поиск: Cellular Responses to AIDS-Virus Infection. Understanding the Antiviral Efficacy and Breadth of CD8+ T Lymphocytes against Simian Immunodeficiency Virus
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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