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 Genetic algorithm for haplotyping and block partitioning. A parsimony-based approach
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Genetic algorithm for haplotyping and block partitioning. A parsimony-based approach

автор Nadezhda S. издательство Книга по Требованию Книги
Cтраниц 132        мягкая обложка       
Аннотация:In addition, the algorithm provides scores for the block boundaries which represent measures of strength of the boundaries at specific positions. The proposed algorithm is also used in a new population clustering algorithm, which extracts from the given genotype sample two clusters with substantially different block structures and finds haplotype resolution and block partitioning for each cluster. The multiloculs LD measure (Normalized Entropy Difference) is used as a block identification criterion. The algorithm is based on genetic algorithm approach and the parsimonious principle. The results show that the proposed genetic algorithm provides the accuracy of haplotype decomposition within the range of the same indicators shown by the other algorithms. The proposed algorithm incorporates missing data is a part of the model and allows blocks of arbitrary length. A new algorithm for performing simultaneous haplotype resolution and block partitioning is proposed.
Автор: Nadezhda S.
Издательство: Книга по Требованию
Год:2010
Цена:
2415 руб
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Поиск: Genetic algorithm for haplotyping and block partitioning. A parsimony-based approach
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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