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 Deformable Microparticles with Multiple Functions for Drug Delivery. Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles
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Deformable Microparticles with Multiple Functions for Drug Delivery. Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles

автор Taili T. издательство Книга по Требованию Прочие виды транспорта
Cтраниц 132        мягкая обложка       
Аннотация:Finding new approaches to develop more efficient blood substitutes will not only bring valuable advances in the clinical approach, but also in the area of in vitro testing of medical devices. Since the HIV epidemic of the 1990s, researchers have attempted to develop a red blood cell analog. Even though some of these substitutes are now in Phase III of clinical trials, their use is limited by side effects and short half-life in the human body. As a preliminary evaluation, different types of microcapsules were synthesized using natural and synthetic polymers, various cross-linking agents, and diverse manufacturing techniques. As a result, there is still a need for an effective erythrocyte analog with minimum immunogenic and side effects, so that it can be used for multiple applications. After fully characterizing of each system, the most promising red blood cell analog in terms of deformability, stability and toxicity was determined. This work examined the feasibility of creating a deformable multi-functional, biodegradable, biocompatible particle for applications in drug delivery and device testing.
Автор: Taili T.
Издательство: Книга по Требованию
Год:2008
Цена:
2415 руб
Нет в наличии
Поиск: Deformable Microparticles with Multiple Functions for Drug Delivery. Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
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