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 Novel Therapeutic Agents for the Treatment of Prostate Cancer. Design and Development of Novel Anti-androgens, Thapsigargin Analogs and Inhibitors of Prostate Specific Antigen
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Novel Therapeutic Agents for the Treatment of Prostate Cancer. Design and Development of Novel Anti-androgens, Thapsigargin Analogs and Inhibitors of Prostate Specific Antigen

автор pratap s. издательство Книга по Требованию Медико-биологические дисциплины
Cтраниц 196        мягкая обложка       
Аннотация:Specifically, we have discovered and designed a diverse array of novel molecules targeting the AR signaling pathway, the sarco-endoplasmic reticulum calcium ATPase pump driven calcium homeostasis and the proteolytic activity of prostate specific antigen . To develop effective therapies against hormone-refractory prostate cancer, novel agents targeting multiple points at the cellular signaling cascades are needed in order to produce the maximal therapeutic efficacy against late stage prostate cancer. In this dissertation work, we have presented the design and development of novel agents targeting three key signaling pathways towards their ultimate development into the effective therapies against hormone refractory prostate cancer. Standard hormonal therapy with currently available anti-androgens and LHRH analogs becomes ineffective in the hormone-refractory stage of prostate cancer due to the changes in androgen receptor signaling axis in prostate cancer cells.
Автор: pratap s.
Издательство: Книга по Требованию
Год:2008
Цена:
2783 руб
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Поиск: Novel Therapeutic Agents for the Treatment of Prostate Cancer. Design and Development of Novel Anti-androgens, Thapsigargin Analogs and Inhibitors of Prostate Specific Antigen
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
Ортомолекулярная медицина Orthomol Устрание причин заболеваний. Ортомоль это новый метод для лечения и профилактики болезней. Orthomol - ортомолекулярная медицина.
Дипломная работа: Выставка как PR-технология в формировании эстетических вкусов и потребностей...

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