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 Structure-function study and engineering of eubacterial flagellin. Eubacterial flagellin engineering
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Structure-function study and engineering of eubacterial flagellin. Eubacterial flagellin engineering

автор Venkata R. M. издательство Книга по Требованию Общая биология
Cтраниц 284        мягкая обложка       
Аннотация:This makes it possible to insert different proteins and peptides in the middle domain and display them on surface of the fiber. In the past few decades biology has been revolutionized by the advances in molecular biology and genetic engineering. This work explores the feasibility of engineering the flagellin protein of Salmonella typhimurium to display proteins/peptides and create bio-nanotubes. Flagellin protein that forms the fiber is the major component of bacterial flagellar system. Bacterial systems have been in the forefront of this revolution and our understanding of life has been extended by their genetic manipulation. The central domain of the protein that is exposed to the periphery of the fiber is highly variable and can be deleted to a large extent. Due to its abundance and export to the cell surface it forms an ideal platform for displaying desired proteins/ peptides. Such system can have important applications in the display of commercially important proteins/peptides, antibody epitopes and bio-degrading enzymes. The current work also explores the protein structure of hyperthermostable flagellin that can serve as a thermostable display system.
Автор: Venkata R. M.
Издательство: Книга по Требованию
Год:2009
Цена:
3233 руб
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Поиск: Structure-function study and engineering of eubacterial flagellin. Eubacterial flagellin engineering
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
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