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 Erbliche Polyposis-Syndrome des Magendarmtraktes. Genetische Untersuchungen zur Aufklaerung der Heterogenitaet adenomatoeser Polyposis-Syndrome
Наименование:

Erbliche Polyposis-Syndrome des Magendarmtraktes. Genetische Untersuchungen zur Aufklaerung der Heterogenitaet adenomatoeser Polyposis-Syndrome

автор Stefan A. издательство Книга по Требованию Книги
Cтраниц 80        мягкая обложка       
Аннотация:Monogen erbliche adenomatoese Polyposis-Syndrome des Magendarm-traktes sind fuer nahezu 1% aller Faelle von Dickdarmkrebs verantwortlich. Es handelt sich um Arbeiten der humangenetischen Grund-lagenforschung, die sich an medizinisch relevanten Aspekten der Krankheitsbilder orientieren und erst durch die Groesse des langjaehrig erschlossenen Patientenkollektivs moeglich wurden. Ein weiterer Schwerpunkt war die genetische und phaenotypische Untersuchung der seit Kurzem bekannten MUTYH-assoziierten Polyposis (MAP). Eine fruehe Diagnose ist entscheidend, da effektive Methoden der Vorsorge und Therapie bestehen. Aufbauend auf grundlegenden Untersuchungen zur familiaeren adenomatoesen Polyposis (FAP) in den 1990er Jahren charakterisieren die in dieser Habilitationsschrift zusam-mengefassten Studien erweiternd und vertiefend verschiedene Muta-tionsarten des APC-Gens und spezielle klinische Manifestationen der FAP. Die Aufklaerung der genetischen Ursachen und Beschreibung der Krankheitsverlaeufe stellt eine wichtige wissenschaftliche Aufgabe dar, die die medizinische Betreuung der Familien verbessert, andererseits aber auch das pathogenetische Verstaendnis des Dick-darmkrebses im Allgemeinen foerdert.
Автор: Stefan A.
Издательство: Книга по Требованию
Год:2010
Цена:
2007 руб
Нет в наличии
Поиск: Erbliche Polyposis-Syndrome des Magendarmtraktes. Genetische Untersuchungen zur Aufklaerung der Heterogenitaet adenomatoeser Polyposis-Syndrome
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