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 Ципрофлоксацин Simultaneous Estimation of Drugs by RP-HPLC. HCl, OFLOXACIN, TINIDAZOLE AND ORNIDAZOLE BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN.
Наименование:

Simultaneous Estimation of Drugs by RP-HPLC. HCl, OFLOXACIN, TINIDAZOLE AND ORNIDAZOLE BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN.

автор Mukesh M. издательство Книга по Требованию Медико-биологические дисциплины
Cтраниц 140        мягкая обложка       
Аннотация:The flow rate was 1. 0 mL. min-1 and the separated drugs were detected using UV detector at the wavelength of 300 nm. The retention time of Ciprofloxacin Hydrochloride, Ofloxacin, Tinidazole, and Ornidazole was noted to be 2. 7, 3. 5, 4. 5 and 5. 8 min, respectively, indicative of rather shorter analysis time. It was successfully applied for the analysis of these drugs in marketed formulations and could be effectively used for the routine analysis of formulations containing any one of the above drugs, or a combination, without any alteration in the chromatographic conditions. A new, simple, rapid, selective, precise and accurate isocratic RP-HPLC assay has been developed for simultaneous estimation of Ciprofloxacin Hydrochloride, Ofloxacin, Tinidazole and Ornidazole in tablet formulations. The separation was achieved by using C-18 column (Phenomenax, 250 x 4. 6mm i. d. ) coupled with a guard column of same material, in mobile phase Acetonitrile: Water: Tri ethylamine (25: 75). The pH of mobile phase was adjusted to 6. 0 ± 0. 1 with 50% ortho phosphoric acid. The method was validated as per ICH guidelines. The proposed method was found to be accurate, reproducible, and consistent.
Автор: Mukesh M.
Издательство: Книга по Требованию
Год:2011
Цена:
2284 руб
Нет в наличии
Поиск: Simultaneous Estimation of Drugs by RP-HPLC. HCl, OFLOXACIN, TINIDAZOLE AND ORNIDAZOLE BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN.
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