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 Function of alpha-crystallin in preventing amorphous and amyloid formation of proteins The Chaperone action of small heat shock protein, alpha-crystallin.
Наименование:

Function of alpha-crystallin in preventing amorphous and amyloid formation of proteins The Chaperone action of small heat shock protein, alpha-crystallin.

автор Arezou G. издательство Книга по Требованию Книги
Cтраниц 296        мягкая обложка       
Аннотация:? -Crystallin is the principal lens protein. In this book in order to better understand the chaperone activity of ? - crystallin under conditions more closely resembling the intracellular environment, its interaction with a range of destabilized proteins in the presence of dextran (68 kDa)have been examined. The concentration of macromolecules inside a cell is very high (up to 300 mg/mL). Macromolecular crowding is ubiquitous in all types of cells and describes the normal conditions inside a cell. In vitro, much work has been published on the interactions of ? -crystallin with target proteins in dilute solutions. It is a member of the small heat shock protein family (sHsp) and acts as a molecular chaperone by stabilizing proteins under stress conditions through the formation of a soluble sHsp target protein complex to prevent their aggregation. This book will be very warmly welcomed by scholars of regional science, biochemist, biophysics, proteomics as well as biologist. Thus, there is a major difference between in vivo and in vitro conditions such as those used in most studies of protein behaviour and properties.
Автор: Arezou G.
Издательство: Книга по Требованию
Год:2010
Цена:
3050 руб
Нет в наличии
Поиск: Function of alpha-crystallin in preventing amorphous and amyloid formation of proteins The Chaperone action of small heat shock protein, alpha-crystallin.


ДОСТИГ ЦЕЛИ, А СЧАСТЬЕ НЕ НАСТУПИЛО?


Шарлота Бронте

Лоб как будто говорит: «Я могу жить одна, если уважение к себе и обстоятельства этого потребуют». Рочестрер делает общий вывод: « he forehead declares, `Reaso si s firm a d holds he rei s, a d will o le he feeli g burs away a d hurry her o wild chasms judgeme hall s ill have he las word i every argume , a d he cas i g vo e i every decisio . S ro g wi d, ear hquake-shock, a d fire may pass by: bu I shall follow he guidi g of ha s ill small voice which i erpres he dic a es of cj scie ce». (этот лоб заявляет: «разум крепко cидит в седле и держит поводья, и не дает чувствам вырваться наружу и увлечь его в пропасть решающее слово в любом споре всегда будет за разумом. Буйные ветры, землетрясения, пожары, чтобы мне не угрожало, я буду следовать тихому голосу, который выражает веление совести» (т. 1, с. 305). При описании внешности героини Ш. Бронте использует лексику различной эмоциональной окраски. Так, говоря о первом впечатлении, которое произвела Джейн на Риверсов, она употребляет образные выразительные средства и лексику, подчеркивающую тяжелое состояние героини: сравнение as whi e as clay or dea h (бледна как мел или смерть), такие выражения как a mere spec re (просто привидение), fleshless a d haggard face very bloodless (осунувшееся, изможденное лицо совсем бескровное).
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