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 In vitro liver reconstruction by small hepatocytes. Reconstruction of hepatic organoids with functional bile canaliculi using rat small hepatocytes
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In vitro liver reconstruction by small hepatocytes. Reconstruction of hepatic organoids with functional bile canaliculi using rat small hepatocytes

автор Ryo S. издательство Книга по Требованию Книги
Cтраниц 140        мягкая обложка       
Аннотация:In particular, bile canaliculi (BC) were formed by differentiated SHs. The groups of the differentiated SHs then moved in a coordinated manner to transport the contents of the reconstructed BC, suggesting that the cells acquired a tissue-level function. SHs, isolated from rat livers, were integrated into tissues in culture. Despite their regenerative capability in vivo, functional hepatocytes are difficult to retain in vitro. In terms of organoid formation, the BC formations can be considered as the first step in tissue organization. To expand these organoids, a 3D culture method was developed by stacking the 2D tissues of SHs. This book focuses on the reconstruction of hepatic organoids using small hepatocytes (SHs) i. e. , hepatic progenitor cells. Development of bioartificial livers is an ongoing study for the future therapy of liver diseases. This method allowed us to construct 3D tissues, including functional BC. In conclusion, the combination of SHs and 3D stacked-up culture can contribute to successful reconstruction of tissue-engineered livers. However, recent studies have revealed that hepatic stem/progenitor cells have capabilities to regenerate hepatic organoids in vitro.
Автор: Ryo S.
Издательство: Книга по Требованию
Год:2010
Цена:
2279 руб
Нет в наличии
Поиск: In vitro liver reconstruction by small hepatocytes. Reconstruction of hepatic organoids with functional bile canaliculi using rat small hepatocytes
НОВЫЙ ГОД СИМВОЛ 2013 ГОДАУКРАШЕНИЯ
КАРНАВАЛ НА НОВЫЙ ГОД РАСПРОДАЖА
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