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 New Inside Out Intermediate Workbook without Key
Наименование:

New Inside Out Intermediate Workbook without Key (+ Audio CD)

автор Sue K. издательство Macmillan Publishers Практические курсы английского языка. Самоучители
Cтраниц 80        мягкая обложка       
Аннотация:Sue and Vaughan have gone back to the classroom to write this new edition, working with teachers and students to find out exactly what works in the real world. The result is one of the most relevant and exciting general English courses available. - Supports the work covered in the Student’s Book and provides extra practice and revision for each unit. - Provides extra listening practice and comes packed with an audio CD - Includes a complete self-contained writing course - A complete story for extra reading practice is included in the back of each workbook. New Inside Out takes all the best elements of the original Inside Out series - including the emphasis on personalisation and meaning - and adds a host of brand-new features.
Автор: Sue K.
Издательство: Macmillan Publishers
Год:2009
Цена:
1115 руб
Количество
Поиск: New Inside Out Intermediate Workbook without Key (+ Audio CD)



Клонирование и анализ генов легких цепей иммуноглобулинов...

Обозначения: - сигнальные олигомеры, фланкирующие V и J сегменты.резкого сокращения количества C генов. В-третьих, подобная организация позволяет упростить регуляцию экспрессии различных локусов. Ключевым принципом функционирования иммунной системы является принцип клональной селекции иммунокомпетентных клеток, несущих рецептор определенной специфичности. Ряд косвенных данных позволяет считать, что у акул гуморальный иммунный ответ клонально ограничен (Sha key a d Clem, 1980). Однако неизвестно, каким образом и насколько эффективно осуществляется это ограничение (Flaj ik, 1996). У млекопитающих принцип “одна клетка - одно антитело” обеспечивается благодаря изотипическому и аллельному исключению. При сегментарной организации генов продуктивная перестройка в одном из локусов ведет к блокированию перестройки других локусов и, тем самым к их инактивации. Однако, в случае наличия множественных VJC кластеров, в части из которых VJ сегменты слиты в зародышевой ДНК, механизмы контроля выборочной экспрессии могут быть более сложными или не столь эффективными.
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